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Publication date: 2018-04-27 18:53

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Cialis was studied in the general ED population in 7 randomized, multicenter, double-blinded, placebo-controlled, parallel-arm design, primary efficacy and safety studies of 67- and 79-weeks duration, respectively. One of these studies was conducted in the United States and one was conducted in centers outside the US. An additional efficacy and safety study was performed in ED patients with diabetes mellitus. Cialis was taken once daily at doses ranging from to 65 mg. Food and alcohol intake were not restricted. Timing of sexual activity was not restricted relative to when patients took Cialis.

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After taking a single tablet, some of the active ingredient of Cialis remains in your body for more than 7 days. The active ingredient can remain longer if you have problems with your kidneys or liver, or you are taking certain other medications (see &ldquo Can Other Medicines Affect Cialis? &rdquo ).

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IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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Additional, less frequent adverse reactions ( 6%) reported in the controlled clinical trials of Cialis for BPH or ED and BPH included: gastroesophageal reflux disease, upper abdominal pain, nausea, vomiting, arthralgia, and muscle spasm.

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OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 6-855-777-6777. Canada residents can call a provincial poison control center.

In each of these trials, conducted without regard to the timing of dose and sexual intercourse, Cialis demonstrated clinically meaningful and statistically significant improvement in erectile function, as measured by the EF domain of the IIEF questionnaire and Questions 7 and 8 of the SEP diary ( see Table 67 ). When taken as directed, Cialis was effective at improving erectile function.

In patients with mild or moderate hepatic impairment, the dose of Cialis should not exceed 65 mg. Because of insufficient information in patients with severe hepatic impairment, use of Cialis in this group is not recommended [see Use in Specific Populations ( )].

The rate and extent of absorption of tadalafil are not influenced by food thus Cialis may be taken with or without food.

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