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Clathrin proteins are involved in building coats for small vesicles. In this image, the clathrin proteins are unraveling to release the vesicle and its contents.

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Lifestyle drugs like Viagra and Cialis have been an extraordinary success for drug companies for many years. It will be difficult to replace the revenue of these blockbuster drugs once they go off patent in the United States, but when that happens consumers can expect generics to race into the marketplace and for prices to fall. The real question, however, is whether . patent law and policy will continue to give pharmaceutical companies the incentives necessary to innovate lifesaving medicines, or whether we will continue to see more and more blockbuster lifestyle drugs moving into the future.

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