Publication date: 2018-04-29 11:41
In patients with mild to moderate hepatic impairment (Child-Pugh A and B), the clearance of vardenafil was reduced in proportion to the degree of hepatic impairment. In patients with mild hepatic impairment (Child-Pugh A), the mean AUC and C max increased 67% and 77% respectively, compared to healthy control subjects. In patients with moderate impairment (Child-Pugh B), the mean AUC and C max increased by 665% and 688% respectively, compared to healthy control subjects (see section ). The pharmacokinetics of vardenafil in patients with severely impaired hepatic function (Child-Pugh C) has not been studied (see section ).
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Tolerability of the maximum dose of 75 mg may be lower in elderly patients ( 8855 65 years old) (see sections and ).
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The most common side effects of VIAGRA: headache flushing upset stomach abnormal vision, such as changes in color vision
(such as having a blue color tinge) and blurred vision stuffy or runny nose back pain muscle pain nausea dizziness rash.
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